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AN35.1-10 | Deep structures in the neck — Part 3

Cervical Rib and Thoracic Outlet Syndrome (AN35.9)

Thoracic Outlet Syndrome — Neurogenic vs Vascular

Feature Neurogenic TOS Vascular TOS
Structure compressed Lower trunk of brachial plexus (C8-T1) Subclavian artery
Symptoms Ulnar border pain, intrinsic muscle wasting, weak grip Upper limb ischaemia, Raynaud's, cold fingers
Signs Thenar and hypothenar wasting, sensory loss C8-T1 Absent radial pulse, positive Adson's test, aneurysm
Frequency More common (95%) Rare (5%)
Treatment Physiotherapy first; surgical rib resection if refractory Surgical rib resection + vascular repair

Cervical rib:
- Anomalous rib arising from C7 vertebra (0.5–1% population; bilateral in 50%; more symptomatic in women)
- Articulates with the 1st rib anteriorly (complete) or terminates in fibrous band (incomplete)
- Compresses the lower trunk of the brachial plexus (C8, T1) and/or the subclavian artery (Part 3)

Cervical Rib and Thoracic Outlet Syndrome (AN35.9)

Figure: Cervical Rib and Thoracic Outlet Syndrome (AN35.9)

Cervical rib and TOS: C7 rib compressing lower trunk and subclavian artery, neurogenic vs vascular TOS clinical features, and Adson's test for diagnosis

Thoracic Outlet Syndrome — Neurogenic vs Vascular

Feature Neurogenic TOS Vascular TOS
Structure compressed Lower trunk of brachial plexus (C8, T1) Subclavian artery or vein
Prevalence ~95% of cases ~5% of cases
Presentation Wasting of small muscles of hand (thenar > hypothenar), pain along medial forearm Pallor, coolness, claudication (arterial); arm swelling, cyanosis (venous)
Key test Adson test (turn head to affected side, deep breath) Elevated arm stress test, arteriography
Treatment Physiotherapy first; surgical excision of cervical rib if refractory Surgical decompression, vascular repair

Thoracic Outlet Syndrome (TOS) — two types:

TypeStructure compressedPresentation
Neurological (more common)Lower trunk (C8, T1)Wasting + weakness of medial forearm/hand muscles; Hypothenar and thenar wasting (T1 > C8); numbness on medial side of forearm/hand (C8, T1 dermatome)
VascularSubclavian artery/veinIschaemia of arm; Raynaud's in young women; subclavian artery post-stenotic dilation; venous TOS → axillary vein thrombosis (effort thrombosis)

Adson's test: extend the arm, rotate head toward the affected side, deep inspiration → obliterates radial pulse (positive in vascular TOS)

Thoracic Outlet Syndrome (TOS) — two types:

Figure: Thoracic Outlet Syndrome (TOS) — two types:

Side-by-side neurogenic vs vascular TOS: neurogenic with lower trunk compression and hand muscle wasting, vascular with subclavian artery compression and distal embolism, both showing cervical rib relationship to scalene muscles

Treatment: physiotherapy first; surgical resection of cervical rib + fibrous band if refractory.

SELF-CHECK

A. Upper trunk of brachial plexus (C5, C6)

B. Middle trunk of brachial plexus (C7)

C. Lower trunk of brachial plexus (C8, T1)

D. Right phrenic nerve

Reveal Answer

Answer: .

The lower trunk (C8, T1) is the most commonly compressed by a cervical rib. C8, T1 supply the intrinsic hand muscles and the medial cutaneous nerve of forearm. Upper trunk compression (C5, C6) causes Erb's palsy pattern (deltoid, biceps weakness) — not seen here.

SELF-CHECK

A. Right CN III palsy from uncal herniation

B. Interruption of the right cervical sympathetic chain by the Pancoast tumour

C. Right facial nerve palsy

D. Disruption of the hypothalamic sympathetic output

Reveal Answer

Answer: .

Pancoast (superior sulcus) tumour at the lung apex compresses the cervical sympathetic chain → Horner syndrome (ptosis, miosis, anhidrosis). It also often compresses the lower trunk (C8–T1) → wasting of small hand muscles. CN III palsy causes complete ptosis + mydriasis (not miosis) — the opposite pattern.

CLINICAL PEARL

Retropharyngeal abscess — don't miss it: In Indian ENT practice, retropharyngeal abscess (often secondary to TB cervical lymphadenitis or upper respiratory infection in children) presents with fever, neck stiffness, dysphagia, and stridor. The retropharyngeal space lies between the posterior pharyngeal wall and the alar fascia. The danger: infection can spread through the 'danger space' (between alar and prevertebral fasciae) directly into the posterior mediastinum → descending necrotising mediastinitis (mortality >40% without surgery). Diagnosis: lateral soft-tissue X-ray of neck shows widening of the prevertebral soft tissue (>7 mm at C2, or >14 mm at C6 in adults). CT neck with contrast is definitive. Treatment: urgent surgical drainage + IV antibiotics + airway management.