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AN57.1-5 | Spinal Cord — Glossary
Cervical enlargement
Widening of the spinal cord at C4-T1 where the large anterior horns contain motor neurons for the upper limb via the brachial plexus
Lumbar enlargement
Widening of the spinal cord at L1-S3 where the motor neurons supply the lower limb via the lumbar and sacral plexuses
Conus medullaris
Cone-shaped terminal end of the spinal cord at L1-L2 in adults and L2-L3 in neonates
Cauda equina
Bundle of lumbar and sacral nerve roots below the conus medullaris resembling a horse's tail; freely floating in CSF
Posterior columns
Fasciculus gracilis and fasciculus cuneatus carrying fine touch, vibration, and proprioception ipsilaterally to the medulla where they cross
Spinothalamic tract
Ascending tract carrying pain and temperature; crosses 1-2 segments above entry in the anterior commissure; ascends contralaterally
Lateral corticospinal tract
Major descending motor tract; 85% of fibres cross at the pyramidal decussation; controls voluntary skilled movements contralaterally
Brown-Sequard syndrome
Hemisection of the cord causing ipsilateral motor loss and proprioception loss with contralateral pain/temperature loss
Syringomyelia
Fluid-filled cavity (syrinx) in the central canal destroying crossing spinothalamic fibres; causes bilateral cape-like loss of pain/temperature
Subacute combined degeneration
Demyelination of posterior columns and lateral corticospinal tracts from vitamin B12 deficiency; loss of proprioception plus spastic paraplegia
Rexed laminae
Ten layers (I-X) of grey matter in the spinal cord; I-IV sensory, VII intermediate with Clarke's column, VIII-IX motor, X pericentral
Clarke's column
Nucleus dorsalis in lamina VII at T1-L2/L3; origin of the posterior spinocerebellar tract carrying unconscious proprioception
Anterior horn cell
Alpha motor neuron in lamina IX; the lower motor neuron that directly innervates skeletal muscle via the ventral root
UMN signs
Upper motor neuron lesion features: spastic paralysis, hyperreflexia, positive Babinski, clonus, no significant wasting
LMN signs
Lower motor neuron lesion features: flaccid paralysis, areflexia, fasciculations, significant muscle wasting, negative Babinski
Babinski sign
Extensor plantar response (great toe dorsiflexion with fanning of other toes) on stroking the lateral sole; indicates UMN lesion in adults
Pyramidal decussation
Crossing of 85% of corticospinal fibres at the caudal medulla; explains why brain lesions cause contralateral motor deficits
Fasciculus gracilis
Posterior column tract medially carrying fine touch and proprioception from the lower limb (below T6); synapses in nucleus gracilis in the medulla
Fasciculus cuneatus
Posterior column tract laterally carrying fine touch and proprioception from the upper limb (above T6); synapses in nucleus cuneatus
Spinal shock
Transient loss of all spinal reflexes below the level of acute spinal cord injury; lasts days to weeks before reflexes return
Neurogenic shock
Loss of sympathetic vasomotor tone from high spinal cord injury (above T6); causes hypotension and bradycardia with warm peripheries
Substantia gelatinosa
Dense small neurons at the tip of the posterior horn (lamina II); modulates pain transmission; site of action of enkephalins and endorphins
ASIA grading
Standardised classification of spinal cord injury severity from A (complete) to E (normal motor and sensory function)