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PY11.1-7 | Special Senses — Glossary
Olfaction
The sense of smell; detection of airborne volatile chemical molecules by receptors in the olfactory epithelium
Olfactory receptor cell (ORC)
A modified bipolar neuron in the olfactory epithelium that detects odorant molecules via G-protein coupled receptors on its cilia
Cribriform plate
The perforated bony plate of the ethmoid bone through which olfactory nerve fibres pass from the nasal cavity to the olfactory bulb
Gustation
The sense of taste; detection of dissolved chemical substances by taste receptor cells in taste buds
Taste bud
A cluster of 50-100 taste receptor cells located mainly in the papillae of the tongue that transduce chemical stimuli into neural signals
Umami
The fifth basic taste quality elicited by L-glutamate and nucleotides, signalling protein-rich food; detected by T1R1+T1R3 receptors
Tympanic membrane
The eardrum; a thin, semi-transparent membrane separating the outer ear from the middle ear that vibrates in response to sound waves
Ossicular chain
The three middle ear bones (malleus, incus, stapes) that transmit and amplify sound vibrations from the tympanic membrane to the oval window
Cochlea
The spiral-shaped structure of the inner ear containing the organ of Corti, responsible for converting sound vibrations into nerve impulses
Organ of Corti
The sensory receptor organ for hearing located on the basilar membrane, containing inner and outer hair cells that transduce mechanical vibrations into electrical signals
Basilar membrane
The membrane within the cochlea that vibrates in response to sound; its width and stiffness vary from base (high frequency) to apex (low frequency), creating tonotopic organisation
Endolymph
The potassium-rich fluid filling the scala media (cochlear duct) and the membranous labyrinth of the vestibular system; its high K+ concentration drives hair cell transduction
Vestibular apparatus
The portion of the inner ear (three semicircular canals, utricle, saccule) responsible for detecting head position and movement for balance and equilibrium
Semicircular canals
Three fluid-filled loops (anterior, posterior, lateral) oriented in three planes that detect angular (rotational) acceleration of the head
Sensorineural deafness
Hearing loss caused by damage to the cochlear hair cells or the cochlear nerve (CN VIII), characterised by Rinne-positive test and Weber lateralising to the normal ear
Conductive deafness
Hearing loss caused by impaired sound transmission through the outer or middle ear, characterised by Rinne-negative test and Weber lateralising to the affected ear
Rinne test
A tuning fork test comparing air conduction (AC) with bone conduction (BC); normally AC > BC (positive); in conductive deafness BC > AC (negative)
Retina
The innermost layer of the eye containing photoreceptors (rods and cones) that convert light into neural signals transmitted via the optic nerve
Rhodopsin
The visual pigment in rod photoreceptors composed of opsin protein and 11-cis retinal (derived from vitamin A); bleaches on light absorption to initiate phototransduction
Fovea centralis
The central depression of the macula containing only cones at highest density, responsible for sharp central vision and colour perception
Accommodation
The process by which the lens increases its refractive power (becomes more convex) to focus on near objects, achieved by contraction of the ciliary muscle and relaxation of zonular fibres
Myopia
Short-sightedness; a refractive error where the eyeball is too long or the cornea too curved, causing distant images to focus in front of the retina; corrected with concave (diverging) lenses
Presbyopia
Age-related loss of lens accommodation due to decreased lens elasticity, causing difficulty focusing on near objects; onset typically after age 40
Visual pathway
The neural route from retina to visual cortex: optic nerve → optic chiasm (nasal fibres cross) → optic tract → lateral geniculate nucleus → optic radiation → primary visual cortex (area 17)
Colour blindness
Deficiency in colour perception due to absence or dysfunction of one or more cone types; most commonly X-linked red-green colour blindness (protanopia or deuteranopia)