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RD7.{1,6} | Imaging in Obstetrics, Gynecology and Breast Care — Glossary

Glossary — RD7.{1,6} | Imaging in Obstetrics, Gynecology and Breast Care

Key terms in this module. Tap a term to see its definition.

Androgen-secreting tumour

An ovarian or adrenal tumour producing excess androgens; suspected when virilisation is rapid or severe with markedly raised testosterone, and investigated with pelvic ultrasound and cross-sectional imaging (MRI/CT) rather than treated as PCOS.

Antral follicle count (AFC)

The ultrasound count of small 2-10 mm follicles across both ovaries in the early follicular phase; a marker of ovarian reserve, with a low count indicating diminished reserve.

Axillary lymph nodes

The principal lymphatic drainage of the breast; their involvement is central to breast-cancer staging and is assessed by ultrasound (with image-guided sampling of suspicious nodes) to guide surgical and systemic treatment.

BI-RADS

Breast Imaging Reporting and Data System — a standardised reporting scheme with assessment categories 0-6, each carrying a defined management recommendation, used to communicate breast imaging findings unambiguously.

BI-RADS category 4-5

Category 4 = suspicious (biopsy should be considered); category 5 = highly suggestive of malignancy (biopsy and appropriate action); both prompt image-guided core biopsy for tissue diagnosis.

BRCA1/BRCA2

Tumour-suppressor genes whose pathogenic mutations markedly raise breast (and ovarian) cancer risk; carriers are offered MRI-based high-risk screening, often alongside mammography, because of their elevated and earlier-onset risk.

Breast density

The proportion of glandular/fibrous (radio-opaque) tissue in the breast; high density (common in younger women) reduces mammographic sensitivity because cancer and dense tissue both appear white, favouring ultrasound or MRI.

Breast MRI

Gadolinium-enhanced magnetic resonance imaging of the breast; the most sensitive modality, used for high-risk screening (e.g. BRCA carriers), staging/extent of disease, equivocal cases and implant assessment; no ionising radiation but lower specificity.

Breast ultrasound

Radiation-free imaging that characterises a breast lesion as solid or cystic and assesses its margins; the first-line imaging for a lump in young women (<~40), in dense breasts, and in pregnancy/lactation, and used to guide biopsy.

Cornual spasm

Transient contraction of the uterine cornu during HSG that prevents contrast entering the proximal tube and mimics a true proximal block — a recognised false positive that must be confirmed before management.

Discriminatory zone

The serum beta-hCG level (~1500-2000 IU/L for transvaginal ultrasound) above which an intrauterine gestational sac should normally be visible if the pregnancy is intrauterine; an empty uterus above this level is suspicious for ectopic or non-viable pregnancy.

Double decidual sign

Two concentric echogenic rings around an eccentrically implanted early intrauterine gestational sac, a supportive feature of a true intrauterine pregnancy distinguishing it from a pseudosac.

Ectopic pregnancy

A pregnancy implanted outside the uterine cavity, most commonly in the fallopian tube (ampulla); the leading cause of first-trimester maternal death, usually from haemorrhage after tubal rupture.

Endometrial thickness

The ultrasound measurement of the endometrial lining; assessed in women with prolonged amenorrhoea and unopposed oestrogen because PCOS carries an increased risk of endometrial hyperplasia.

Follicle number per ovary (FNPO)

The count of 2-9 mm antral follicles in a single ovary on ultrasound; ≥20 (high-frequency probe) or ≥12 (older equipment) satisfies the morphological criterion for PCOM.

Follicular tracking

Serial transvaginal ultrasound during ovulation induction to count and measure developing follicles and time ovulation, intercourse or trigger; the active role of imaging in PCOS-related fertility management.

Haemoperitoneum

Blood within the peritoneal cavity, seen on ultrasound as echogenic free fluid; in suspected ectopic pregnancy it signals tubal leakage or rupture and, with haemodynamic instability, mandates emergency surgery.

Heterotopic pregnancy

A coexisting intrauterine and ectopic pregnancy; rare in spontaneous conception but markedly more common after assisted reproduction (IVF), so the adnexa must be examined even when an intrauterine pregnancy is seen.

Hydrosalpinx

A distally blocked, fluid-distended fallopian tube appearing as a sausage-shaped dilated structure; its fluid is toxic to implantation and lowers IVF success, so salpingectomy or occlusion is advised before IVF.

Hyperandrogenism

Clinical (hirsutism, acne, male-pattern hair loss) or biochemical (raised free testosterone / free androgen index) evidence of androgen excess; one of the three Rotterdam criteria for PCOS.

Hysterosalpingo-contrast-sonography (HyCoSy)

An ultrasound-based, radiation-free alternative to HSG that assesses tubal patency by watching the flow of an ultrasound contrast/saline-air medium along the tubes on transvaginal scanning.

Hysterosalpingography (HSG)

A fluoroscopic test in which iodinated contrast is instilled through the cervix to outline the uterine cavity and fallopian tubes; free peritoneal spill confirms tubal patency. Performed in the follicular phase (days 6-10) after excluding pregnancy and active infection.

Image-guided core biopsy

Sampling of a breast lesion under ultrasound, stereotactic mammographic or MRI guidance to obtain tissue for histological diagnosis; the pathology limb of the triple assessment for BI-RADS 4-5 lesions.

Infertility

Failure to conceive after twelve months of regular unprotected intercourse (or six months if the woman is over 35 or there is a known risk factor); evaluated across ovarian, tubal and uterine factors plus the male factor.

Interstitial (cornual) ectopic

An ectopic pregnancy implanted in the interstitial (cornual) portion of the tube within the uterine wall, with a thin surrounding myometrial mantle; prone to late, catastrophic rupture.

Intrauterine adhesions (Asherman syndrome)

Bands of scar tissue within the uterine cavity, often following instrumentation, causing light periods and infertility; seen on SIS/hysteroscopy as bridging bands or a partly obliterated cavity and corrected hysteroscopically.

Laparoscopy with chromopertubation

The definitive, gold-standard test of tubal patency in which methylene-blue dye is instilled and spill from the fimbrial ends is observed directly; also visualises endometriosis and adhesions.

Mammography

Low-dose X-ray imaging of the compressed breast (standard craniocaudal and mediolateral-oblique views); the screening modality for breast cancer, especially good at detecting microcalcifications, with reduced sensitivity in dense breasts.

Methotrexate (medical management)

A folate-antagonist chemotherapeutic used to treat selected stable, unruptured ectopic pregnancies with low beta-hCG, no fetal cardiac activity and small mass, with response monitored by serial beta-hCG.

Microcalcifications

Tiny calcium deposits on mammography; clustered, pleomorphic or fine branching/linear microcalcifications are suspicious for malignancy (especially ductal carcinoma), whereas coarse or rim calcifications are usually benign.

Mullerian anomaly

A congenital uterine malformation (e.g. septate, bicornuate, unicornuate uterus) characterised by 3D ultrasound or MRI using the external fundal contour to distinguish septate from bicornuate, an important distinction for management.

Multifollicular ovary

A normal ovary containing several follicles of variable size distributed throughout, with normal volume — physiologically common in adolescents and the early follicular phase; it is NOT polycystic ovarian morphology.

Oligo-ovulation / anovulation

Infrequent or absent ovulation, manifesting clinically as oligomenorrhoea or amenorrhoea; one of the three Rotterdam criteria for PCOS.

Ovarian reserve

The quantity of remaining oocytes, reflected by the antral follicle count and serum anti-Mullerian hormone (AMH); diminished reserve adds urgency to fertility counselling and treatment.

Ovarian volume

Ovarian size calculated as 0.523 × length × width × height; a volume >10 mL in either ovary (without a dominant follicle, cyst or corpus luteum) satisfies the PCOM criterion and is the criterion of choice when follicles cannot be counted reliably.

Polycystic ovarian morphology (PCOM)

The ultrasound appearance of a polycystic ovary: ≥20 follicles of 2-9 mm per ovary on a high-frequency transducer (or ≥12 on older equipment) and/or ovarian volume >10 mL in at least one ovary.

Polycystic ovary disease (PCOD/PCOS)

A common endocrine disorder of reproductive-age women characterised by oligo/anovulation, hyperandrogenism and/or polycystic ovarian morphology, with associated metabolic risk; diagnosed by the Rotterdam criteria.

Pouch of Douglas

The rectouterine pouch, the most dependent part of the female pelvis; free fluid here is assessed on ultrasound — echogenic fluid suggests haemoperitoneum from a leaking or ruptured ectopic.

Pregnancy of unknown location (PUL)

A positive pregnancy test with neither an intrauterine nor an extrauterine pregnancy visible on transvaginal ultrasound; a temporary classification resolved by serial beta-hCG and repeat scanning, never discharged as 'normal'.

Pseudogestational sac

A central fluid collection within the endometrial cavity that can accompany an ectopic pregnancy and mimic an intrauterine sac; distinguished by its central position, absent double decidual sign and absent yolk sac.

Rotterdam criteria

The 2003 ESHRE/ASRM consensus criteria for PCOS: a diagnosis requires any TWO of three features — oligo/anovulation, clinical or biochemical hyperandrogenism, and polycystic ovarian morphology on ultrasound — after excluding mimics.

Saline infusion sonohysterography (SIS)

Distension of the uterine cavity with sterile saline during transvaginal ultrasound to delineate endometrial polyps, submucous fibroids, intrauterine adhesions and a septum.

Salpingectomy / salpingotomy

Surgical removal of the affected fallopian tube (salpingectomy) or incision and evacuation of the ectopic while conserving the tube (salpingotomy); the surgical options for ectopic pregnancy, usually performed laparoscopically.

Screening

The detection of disease in asymptomatic people before symptoms appear, aiming to reduce mortality; breast screening uses mammography in defined age ranges and balances benefit against harms such as false positives and overdiagnosis.

Serum beta-hCG

Beta subunit of human chorionic gonadotrophin secreted by trophoblast; in early pregnancy it reflects trophoblastic mass (not location) and is interpreted alongside ultrasound and against the discriminatory zone.

Spiculated mass

A mass with radiating linear margins on mammography or ultrasound, a feature highly suspicious for invasive malignancy because of the infiltrative growth of cancer into surrounding tissue.

Staging imaging (CT / bone scan / PET-CT)

Cross-sectional and nuclear imaging used to detect distant metastatic spread (lung, liver, bone) in higher-stage or symptomatic breast cancer; these stage disease and do not detect the breast primary, which is assessed by mammography, ultrasound and MRI.

String of pearls

The descriptive ultrasound appearance of a polycystic ovary in which numerous small uniform follicles are arranged peripherally around increased central stroma.

Submucous fibroid

A uterine leiomyoma projecting into or indenting the endometrial cavity, seen as a cavity-distorting hypoechoic mass on TVS/SIS; may impair implantation and is treated hysteroscopically.

Transabdominal ultrasound (TAS)

Ultrasound of the pelvis performed through the abdominal wall and a full bladder; used when transvaginal scanning is not feasible, with ovarian volume rather than follicle count as the reliable morphological criterion due to lower resolution.

Transvaginal ultrasound (TVS)

Ultrasound performed with a high-frequency endovaginal probe placed close to the pelvic organs; the first-line modality for assessing ovarian morphology in sexually active women because of its superior spatial resolution.

Triple assessment

The integrated evaluation of a breast lesion by clinical examination, imaging (mammography and/or ultrasound), and pathology (core biopsy or FNAC); concordance between the three gives a reliable diagnosis, and discordance is always investigated further.

Tubal patency

Openness of the fallopian tubes allowing egg and sperm to meet; assessed by HSG, HyCoSy or laparoscopy with dye, with free peritoneal spill of contrast/dye indicating a patent tube.

Tubal ring sign

An adnexal echogenic ring with a hypoechoic centre ('bagel'/'donut') lying separate from the ovary on ultrasound; a highly specific direct sign of a tubal ectopic pregnancy.

54 terms in this module